Windows 7 (and therefore vvvv) is running perfectly fine on the Mac. The biggest annoyance is that you always need a three button mouse attached to interact flawlessly.
I’d even dare to presume that the MacBook is the most popular piece of hardware where vvvv is run. (In the classes I teach the share is always around 70-80%)
My 2 cents from the opposite of the anything-but-Apple scope.